P13 The Overlapping Prevalence Of Chronic Mucus Hypersecretion (cmh) And Chronic Cough (cc)
نویسندگان
چکیده
منابع مشابه
Susceptibility to Chronic Mucus Hypersecretion, a Genome Wide Association Study
BACKGROUND Chronic mucus hypersecretion (CMH) is associated with an increased frequency of respiratory infections, excess lung function decline, and increased hospitalisation and mortality rates in the general population. It is associated with smoking, but it is unknown why only a minority of smokers develops CMH. A plausible explanation for this phenomenon is a predisposing genetic constitutio...
متن کاملDissecting the genetics of chronic mucus hypersecretion in smokers with and without COPD.
Smoking is a notorious risk factor for chronic mucus hypersecretion (CMH). CMH frequently occurs in chronic obstructive pulmonary disease (COPD). The question arises whether the same single-nucleotide polymorphisms (SNPs) are related to CMH in smokers with and without COPD. We performed two genome-wide association studies of CMH under an additive genetic model in male heavy smokers (≥20 pack-ye...
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Cough that remains unexplained after basic clinical assessment is a common reason for referral to secondary care. Much of the evidence about management of isolated chronic cough is derived from case series; this evidence suggests that isolated chronic cough is usually due to asthma, gastro-oesophageal refl ux disease, and upper airway conditions, and that it can be cured in most people by treat...
متن کاملClinical significance of airway mucus hypersecretion in chronic obstructive pulmonary disease
Airway mucus hypersecretion is one of the most important features of chronic obstructive pulmonary disease (COPD). Airway mucus hypersecretion in COPD patients results in outcomes such as rapid decline of lung function, poor quality of life, and high rate of acute exacerbation, hospitalization and mortality. Nonpharmacologic treatments for airway mucus hypersecretion in COPD include smoking ces...
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ژورنال
عنوان ژورنال: Thorax
سال: 2014
ISSN: 0040-6376
DOI: 10.1136/thoraxjnl-2014-206260.163